Changes in version 0.1.6 - A logical variable has been implemented to specify whether to include the interaction between time and covariates in the model. Changes in version 0.1.5 (2025-04-11) - Added the reference of this package. Missing data is automatically removed in bct.v function. Corrected typos in help files of several functions. etc. Changes in version 0.1.4 (2020-03-31) - Added several generic functions for "bcmmrm" and "bcmarg" functions. Changes in version 0.1.3 (2020-03-02) - Revised in accordance with the comments from CRAN: added "verbose" option to the "plot.bcmmrm" and "boxplot.bcmmrm" functions. Changes in version 0.1.2 - Revised in accordance with the comments from CRAN: "Note" in the summary.bcmarg function is displayed by the message function. Changes in version 0.1.1 - Revised in accordance with the comments from CRAN: doi -> url Changes in version 0.1.0 - INITIAL RELEASE (before submitting CRAN): mixed effect model with the Box-Cox transformation.